Check out this recent article in Nature. Here is the first paragraph:
Mutant mice chill out on ecstasy
Drug to prevent lethal overheating may result from protein find.
27 November 2003
HELEN R. PILCHER
Ecstasy causes body temperature to rise.
Mice that lack a key protein stay cool after ingesting ecstasy. Therapies to treat potentially fatal overheating associated with the club drug may follow.
For the full article use this link -
http://www.nature.com/nsu/031124/031124-5.html